Multifunctional Gold Nanostar Probe for Cancer Theranostics
Cancer has become a significant threat to human heath and results in more than eight million deaths each year. Early detection and specific therapy could improve cancer patients’ prognosis. We have developed a novel multifunctional gold nanostar probe for pre-operative scan with PET, MRI and CT, intraoperative margin delineation with optical imaging and surface enhanced Raman spectroscopy (SERS), and cancer treatment with plasmonics enhanced phototherapy. Preclinical studies have shown its great potential for cancer diagnostics and therapeutics for future clinical translation.