Abstract

A novel DNA bioassay-on-chip using surface-enhanced Raman scattering (SERS) on a bimetallic nanowave chip is presented. In this bioassay, SERS signals were measured after a single reaction on the chip's surface without any washing step, making it simple-to-use and reducing the reagent cost. Using the technique, specific oligonucleotide sequences of the dengue virus 4 were detected.

DOI
10.1039/c4an01077a
Year
Chicago Citation
Ngo, Hoan T., Hsin-Neng Wang, Andrew M. Fales, Bradly P. Nicholson, Christopher W. Woods, and Tuan Vo-Dinh. “DNA bioassay-on-chip using SERS detection for dengue diagnosis.” Analyst 139, no. 22 (November 21, 2014): 5655–59. https://doi.org/10.1039/c4an01077a.