• Nanobiosensors

    In 2000, our laboratory developed the first antibody-based nanobiosensor for monitoring biochemical species in a single living human cell [Nature Biotechnology, 18: 764-767 (2000)]. Various nanobiosensors were later developed for monitoring intracellular parameters...

  • SERS Molecular Probes

    In 1994 our laboratory first introduced a new modality for nucleic acid bioassays using SERS detection [Analytical Chemistry, 66, 3379 (1994)]. We further extended the new family of SERS gene probes with the development of ‘Molecular Sentinels’ and Plasmonic Coupling Interference (PCI)...

  • SERS Plasmonic Chips

    In 1984, our laboratory first reported the general applicability of SERS as an analytical technique [Analytical Chemistry, 56: 1667 (1984)]. We also first introduced the use of metal film on nanostructures (MFON), referred to as 'nanowave', as efficient and reproducible plasmonics-active media.

  • Gold Nanostar for Molecular Imaging and Cancer Therapy

    Gold nanostars exhibit a unique star shape and several interesting photonic properties that can be exploited for molecular imaging and cancer therapy. Read more

  • THERANOSTICS: Two-photon Photoluminescence Imaging & Photothermal Therapy

    Two-photon photoluminescence (TPL) imaging offers a strong optical contrast mechanism for viewing Gold Nanostars in real-time. Read more



The Vo-Dinh Lab is a part of the Department of Biomedical Engineering of the Pratt School of Engineering, and the Chemistry Department of the School of Arts & Science,  Duke University. Together with a number of other research groups, the Vo-Dinh Lab is also a part of the Fitzpatrick Institute for Photonics, of which Professor Vo-Dinh is the director.

Group picture 042915

The Vo-Dinh group (summer 2015)

Research Focus:

The research of the Vo-Dinh Lab is focused on the development of advanced technologies for the protection of the environment and the improvement of human health. The research activities involve biophotonics, nanoplasmonics, nanosensors, laser spectroscopy, molecular imaging, medical diagnostics, cancer detection and therapy, theranostics, chemical sensors, biosensors, and biochips.

Our laboratories are located in the Fitzpatrick Center (FCIEMAS) and the French Family Science Center, both situated on Duke University West Campus.


Fitzpatrick Center (FCIEMAS)



French Family Science Center

Group picture 042915

The Vo-Dinh group (summer 2015)