DNA Biochip

We have recently investigated a new generation of biosensors using DNA probes (DNA Biochip). Probe recognition is based on the molecular hybridization process, which involves the joining of a strand of nucleic acid with a complementary sequence. Biologically active DNA probes are directly immobilized on optical transducers which allow detection of Raman, SERS, or fluorescent probe labels. DNA biosensors could have useful applications in areas where nucleic acid identification is involved. The DNA probes could be used to diagnose genetic susceptibility and diseases. The Biochip using antibody probes has recently been developed to detect the p53 protein system

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